The great obstacle to progress is prejudice
Ideas are like matter, infinitely divisible. It is not given to us to get down so to speak to their final atoms, but to their molecular groupings-the way is never ending and the progress infinitely delightful and profitable.
An ambition to excel in petty things obstructs the progress to nobler aims.
Intellectually, as politically, the direction of all true progress is towards greater freedom, and along an endless succession of ideas.