In shamanic cultures, sychronicities are recognized as signs that you are on the right path.
We live in a culture where everything tastes good but nothing satisfies.
We live in a culture where everything is designed for our comfort or entertainment but nothing satisfies. At our core, we remain insatiable, constantly on the prowl for new commodities and pleasant sensations to fill the void.
A lot of indigenous cultures are deeply involved in working with ancestor spirits, elemental spirits, and demons. Many of these cultures feel that, if you don't deal properly with ancestor spirits, then they come back and infest the living in the form of things like depression, addictive patterns, and neuroses. We in the modern West completely deny the existence of these spirits or other types of entities. And because we've denied them, we may have opened the gates for them to manipulate us in a lot of ways.