It would be so weird if we knew just as much as we needed to know to answer all the questions of the universe. Wouldn't that be freaky? Whereas the probability is high that there is a vast reality that we have no way to perceive, that's actually bearing down on us now and influencing everything.
I still believe that capitalism is too harsh and I believe that, even within that, there is a lot of satisfaction and beauty if you happen to be one of the lucky ones, although that doesn't eradicate the reality of the suffering. It's all true at once, kind of humming and sublime.
In the reason that the contrast between the absolute and the relative is so terrible is because we believe so fully in ourselves as permanent, continuous, and central. I feel insane saying this, but if one weren't so deluded about the permanent reality of the self, a lot of this pain would actually lessen.
My theory for nonfiction is that nobody can be free of some kind of conceptions about whatever story they're writing. But if you can find a way to build those into the story, then the story becomes a process of deconstructing and heightening and sometimes changing those notions and that makes dramatic tension. The initial statement of your position, and then letting reality act on you to change it, is pretty good storytelling.