We live what we know. If we believe the universe and ourselves to be mechanical, we will live mechanically. On the other hand, if we know that we are part of an open universe, and that our minds are a matrix of reality, we will live more creatively and powerfully.
General Systems Theory, a related modern concept [to holism], says that each variable in any system interacts with the other variables so thoroughly that cause and effect cannot be separated. A simple variable can be both cause and effect. Reality will not be still. And it cannot be taken apart! You cannot understand a cell, a rat, a brain structure, a family, a culture if you isolate it from its context. Relationship is everything.
We live what we know. If we believe the universe and ourselves to be mechanical, we will live mechanically.