Granted, we may try to help our own family members because they share our DNA. Or help someone else in expectation that they will help us later. But when you look at what we admire as the most generous manifestations of altruism, they are not based on kin selection or reciprocity. An extreme example might be Oskar Schindler risking his life to save more than a thousand Jews from the gas chambers. That's the opposite of saving his genes.