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The upshot of all this is that we live in a universe whose age we can't quite compute, surrounded by stars whose distances we don't altogether know, filled with matter we can't identify, operating in conformance with physical laws whose properties we don’t truly understand.

FaceBook post by Bill Bryson from Oct 14, 2012
The upshot of all this is that we live in a universe whose age we can't quite compute, surrounded by stars whose distances we don't altogether know, filled with matter we can't identify, operating in conformance with