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Perfectionism is self destructive simply because there's no such thing as perfect. Perfection is an unattainable goal.

Brené Brown (2010). “The Gifts of Imperfection: Let Go of Who You Think You're Supposed to Be and Embrace Who You Are”, p.71, Simon and Schuster
Perfectionism is self destructive simply because there's no such thing as perfect. Perfection is an unattainable goal.