I've never been in a situation where I had to run for my life, but I've been bitten by a lot of poisonous snakes where it was fairly painful. Pythons of size have a lot of teeth in that mouth, it's a painful bite and those wounds get infected fairly easily. I've got snake wounds from these animals that have lasted quite a while where it'll ache for several days. Having said that, I've been lucky; it's not like I'm looking for trouble with these animals either. It's not an envelope I'm willing to push.