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The main difference between commissioned work and work I do for myself is that if I'm doing for myself, I don't have to worry about sticking to an art description or working for a specific audience or project.

Source: littleredreviewer.wordpress.com
The main difference between commissioned work and work I do for myself is that if I'm doing for myself, I don't have to worry about sticking to an art description or working for a specific audience or project.