But some of these theories are so bold that they can clash with reality: they are the testable theories of science. And when they clash, then we know that there is a reality; something that can inform us that our ideas are mistaken.
Karl Popper, W.W. Bartley, III (2013). “Quantum Theory and the Schism in Physics: From the Postscript to The Logic of Scientific Discovery”, p.3, Routledge
