I mean, stand up you're by yourself and it's live and when you're acting, unless you're doing a monologue, you're interacting with somebody else. Even if you're doing a monologue you're saying it to somebody and it's not live so you can do it a few times.
I'm a standup comedian who gets to act. I'm never going to not do standup. I love doing it and when I go through periods where I'm doing a lot of acting work, I still do standup.
Acting in a sitcom or a comedy movie is like a comedy routine with the setups.
