Flourishing is properly the main human end, and flourishing is activity of soul that succeeds in accord with virtue.
Descartes's epistemology is a special case of Aristotle's virtue ethics.
Since human good is what humans ought to pursue, the pursuit of interest to Aristotle is then such activity of soul, that which constitutes human good, namely activity that attains desiderata, where the attainment is in accord with virtue.
Ultimately, my more significant agreement is with a virtue tradition that features Aristotle and Descartes.