Experience as much as you can and absorb a lot of reality. Otherwise, your writing will have the force of a Wiffle ball.
When people have no interest in a subject, it's very hard to get them to laugh about it. If I had to write ten jokes about potholders, I don't think I could do it. But I could write ten jokes about Catholicism in the next twenty minutes.
I don't remember a lot of what I write. I try to release it after it's out there so that I can be fresh again.