People are so busy chasing happiness- if they would slow down and turn around, they would give it a chance to catch up with them.
The circumstances of your life have uniquely qualified you to make a contribution. And if you don't make that contribution, nobody else can make it.
None of us has the power to make someone else love us. But we all have the power to give away love, to love other people. And if we do so, we change the kind of world we live in.
When I talk to people who feel this emptiness and lack of fulfillment, I recommend they find a source of balance in their lives. I suggest they find a way to "give back" to the world in order to feel a sense of completeness.