The human failing I would most like to correct is aggression. It may have had survival advantage in caveman days, to get more food, territory or a partner with whom to reproduce, but now it threatens to destroy us all.
Keeping an active mind has been vital to my survival, as has been maintaining a sense of humor.
Our only chance of long-term survival is not to remain lurking on planet Earth, but to spread out into space.
Although September 11 was horrible, it didn't threaten the survival of the human race, like nuclear weapons do.