Even in populous districts, the practice of medicine is a lonely road which winds up-hill all the way and a man may easily go astray and never reach the Delectable Mountains unless he early finds those shepherd guides of whom Bunyan tells, Knowledge, Experience, Watchful, and Sincere.
Sir William Osler (2001). “Osler's "a Way of Life" and Other Addresses, with Commentary and Annotations”, p.273, Duke University Press