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Nature has placed in the front part of man, as he moves, all those parts which when struck cause him to feel pain; and this is felt in the joints of the legs, the forehead and the nose, and has been so devised for the preservation of man, because if such pain were not felt in these limbs they would be destroyed by the many blows they receive.

Leonardo da Vinci (2013). “Life, art and science, the thoughts of Leonardo”, p.271, Lulu.com
Nature has placed in the front part of man, as he moves, all those parts which when struck cause him to feel pain; and this is felt in the joints of the legs, the forehead and the nose, and has been so devised for the