One of the biggest lessons when it comes to working with friends and family is to have the confidence to fire your mother-in-law if need be. The way to keep issues with loved ones out of the boardroom is to create what I call a start-up prenup, a document that puts the rights and responsibilities of each partner on paper. It's OK to start a business with those you love, but make sure you have a plan if the love goes away. But too often I've seen the dreadful alternative. My advice is formalize your partnership agreement.