Many scales of climate change are in fact natural, from the slow tectonic scale, to the fast changes embedded within glacial and interglacial times, to the even more dramatic changes that characterize a switch from glacial to interglacial. So why worry about global warming, which is just one more scale of climate change? The problem is that global warming is essentially off the scale of normal in two ways: the rate at which this climate change is taking place, and how different the "new" climate is compared to what came before.
Anthony D. Barnosky (2010). “Heatstroke: Nature in an Age of Global Warming”, p.27, Island Press