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Once the pathological low self-esteem goes, that's when things go downhill.

Moby
Self Esteem, Lows, Self
"David Bowie EW Cover: Inside David Bowie and Moby's out-of-this-world 2002 tour". Interview with Jeff Gordinier, ew.com. January 11, 2016.
Once the pathological low self-esteem goes, that's when things go downhill.