Find something you love and commit. Commit 100%. Put your head down, and work as hard as you can. Make it as best you can, and that's all you can really do. It doesn't sound like much, but lots of people don't do the work. And it's not men or women. Lots of people like to be the director, but don't like to do a lot of the work that is sometimes quite tedious.
As a director who does not like to write, I am always looking for scripts that I can contribute to through directing. I don't want to do the same thing that the writer is doing; I want to add an angle or highlight a theme.
For me, when you're casting known talent, you're not just casting their performances. You're casting the public's relationship with them, their public images to a degree.
I sometimes hear people say women don't want to direct studio films, but I do. I want to direct big films, little films, TV. I want to do it all.