Ignorance is a virus. Once it starts spreading it can only be cured by reason. For the sake of humanity, we must be that cure.
For me, I am driven by two main philosophies, know more today about the world than I knew yesterday. And along the way, lessen the suffering of others. You'd be surprised how far that gets you.
God is an ever-receding pocket of scientific ignorance that's getting smaller and smaller and smaller as time moves on.