Thomas Jefferson, the leading Enlightenment figure in the United States, along with Benjamin Franklin, who took exactly the same view, argued that dependence will lead to "subservience and venality", and will "suffocate the germs of virtue". And remember, by dependence he meant wage labor, which was considered an abomination under classical liberal principles.
With the development of industrial capitalism, a new and unanticipated system of injustice, it is libertarian socialism that has preserved and extended the radical humanist message of the Enlightenment and the classical liberal ideals that were perverted into an ideology to sustain the emerging social order.
Libertarian socialism is properly to be regarded as the inheritor of the liberal ideals of the Enlightenment.
Marx's early manuscripts, with their roots in the Enlightenment and Romanticism, derived fundamental concepts such as alienation from a conception of human nature - what we would call genetically determined.