For me, writing is not a search for explanations but a ramble in quest of what informs a place, a hunt for equivalents.
It's difficult to write a book where a character is on virtually every page of the book but you cannot refer to his or her gender. It gets rid of every his, her, she and he.
I contend that in the kind of nonfiction I write, and that other people also pursue, anything is permissible provided the reader knows what you're taking liberties with.