Karma is your survival and your bondage. And if you handle it right, it can also be your liberation.
If you just live totally, you will dissolve lots of karma. Living totally means that you experience anything that comes fully and intensely.
Karma means ultimate responsibility. You even take responsibility for your genetics.
Whether it is suffering or joy, going through experiences in life is not so much of a karma. Depriving yourself of any experience is the big karma.