I try to be careful and put things in perspective. There are people who have challenging lives and work hard physically and mentally. I consider myself a lucky person because I get to go on stage and tell jokes for an hour. If I miss a connection here and there or my room isn't ready now and then? It's not a big deal.
I do a few jokes about the economy but from an everyday person perspective. People like to laugh, and they especially like to laugh during difficult circumstances.
Don't let dialog about your company happen without your perspective.