Blame is a neat little device that you can use whenever you don't want to take responsibility for something in your life. Use it and you will avoid all risks and impede your own growth.
First, imagine taking the potentially regret - producing path of inaction. Then imagine what the very best outcome would be were you to take this risk. By picturing both scenarios in advance, you can avoid the regret of what might have been.
Instead of asking yourself what everyone else's opinion is going to be and how your action will be perceived by others, ask yourself, 'How do I want my life to be lived?' Then proceed to take a small risk in the direction of that new action.