The secrets of alchemy exist to transform mortals from a state of suffering and ignorance to a state of enlightenment and bliss.
Ignorance is constricted awareness.
Addiction is craving fulfillment from something that cannot provide fulfillment. In this sense it is not different than the basic mechanism of ignorance that keeps everyone in bondage. With substance addiction the mind/body sets up a vicious cycle that perpetuates the dependence.